Quiescent affinity inactivators of protein tyrosine phosphatases

DOI: 10.1016/0968-0896(96)00144-7

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1515 - 1520 (1996)

Update date:2022-08-04

Topics:

Authors:

Taylor, William P.

Zhang, Zhong-Yin

Widlanski, Theodore S.

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Article abstract of DOI:10.1016/0968-0896(96)00144-7

-Halobenzylphosphonates were investigated as possible inactivators of protein tyrosine phosphatases (PTPases). These compounds inactivate the Yersinia PTPase (Yop51*Δ162) in a time- and concentration-dependent fashion. This inactivation is active-site dir

Full text of DOI:10.1016/0968-0896(96)00144-7

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