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Design and synthesis of novel DNA interstrand cross-linking agents: C2-linked pyrrolo[2,1-c][1,4]benzodiazepine polyamide conjugates

DOI: 10.1515/HC.2002.8.2.115

Source and publish data:

Heterocyclic Communications p. 115 - 122 (2002)

Update date:2022-08-02

Topics:

Authors:

Kumar, Rohtash

Lown, J. William

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Article abstract of DOI:10.1515/HC.2002.8.2.115

The design and synthesis of C2- linked novel pyrrolo[2,1-c][1,4]benzodiazepine (PBD)-polyamide conjugates (1a - c) as DNA minor groove binding agents are described.

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Full text of DOI:10.1515/HC.2002.8.2.115

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Product name:[(2S,4R)-2-(Bis-ethylsulfanyl-methyl)-4-hydroxy-pyrrolidin-1-yl]-(2-nitro-phenyl)-methanone

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241489-15-6

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