Practical synthesis of optically active bicyclic oxazolidinylpiperidines, chiral building blocks for preparing 1- deoxyazasugars, from serine

Article abstract of DOI:10.1016/S0040-4039(99)00969-7

Optically active bicyclic oxazolidinylpiperidines 1a, 1b, 1c and 1d, known chiral building blocks for preparing 1-deoxyazasugars, were synthesized in high overall yield from D-serine by a method wherein the titanium(II)- mediated intramolecular nucleophil