Chemical and Pharmaceutical Bulletin p. 1545 - 1548 (2000)
Update date:2022-08-03
Topics:
Honda
Endo
Ono
Preparation of 6-substituted 4-hydroxytetrahydro-2H-pyran-2-one (12), a key intermediate for the synthesis of (-)-tetrahydrolipstatin, was achieved in an optically pure form by employing an enantioselective deprotonation reaction of the prochiral bicyclic
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(1970)
