
Tetrahedron Letters p. 8901 - 8904 (1998)
Update date:2022-07-30
Topics:
Richecur, Alexandre M.E.
Sweeney
An unambiguous and highly enantioselective total synthesis of the naturally-occurring 2(5H)-furanone hamabiwalactone B has been achieved. The key step is a Stille coupling of novel stannylfuranone 2 with (E)-iodoalkene 3. The enantiomeric purity of the synthetic natural product was ≥ 99%, as judged by chiral HPLC.
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Doi:10.1039/a905492h
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