
Tetrahedron Letters p. 2047 - 2050 (2000)
Update date:2022-07-30
Topics:
Mugrage, Ben
Diefenbacher, Clive
Somers, Joe
Parker, David T.
Parker, Tonia
The phosphonic acid analog of the NSAID Diclofenac was efficiently synthesized via an Arbuzov reaction between 2-(2,6-dichloroanilino)benzyl alcohol and trimethyl phosphite followed by TMSBr promoted dealkylation. Seven related phosphonic acids were synth
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