Bioorganic and Medicinal Chemistry Letters p. 1843 - 1848 (1996)
Update date:2022-08-03
Topics:
Shinozuka, Kazuo
Yamada, Nobuaki
Nakamura, Akiko
Ozaki, Hiroaki
Sawai, Hiroaki
Rnase H mediated degradation of RNA on the β-DNA·RNA duplex was inhibited by the presence of extra 2'-deoxypyrimidine homooligomer. The effect was dependent on the nature of the nucleobase, glycoside bond configuration, and the internucleotide linkage of the extra homooligomer used. Thus, α-anomeric 2'-deoxycytidylate phosphorothioate exhibited the most potent inhibitory effect (> 40%) on RNase H.
View MoreTianjin SPHINX SCIENTIFIC LAB.
Contact:+86-022-66211289
Address:Tianda high-tech Park. No.80,the 4th Avenue
Suzhou Credit International Trading Co., Ltd
Contact:+86-512-65398039
Address:Qingdeng, Hightech. District, Suzhou
NINGBO PANGS CHEM INT’L CO., LTD.
Contact:+86-0574-27666801
Address:Floor 21, Building 11, Xintiandi, No. 689, Shijiroad, Ningbo, Zhejiang, China
Landz International Company Ltd.
Contact:0086-21-58891610
Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Baicao Pharmaceutical Co., Ltd.
website:http://www.jxbaicao.com
Contact:+86-796-8113329
Address:It (country) economic and technological development zone of the jinggang mountains
Doi:10.1021/ja994522u
(2000)Doi:10.1021/ol0166909
(2001)Doi:10.1016/j.molcatb.2011.07.019
(2011)Doi:10.1016/S0968-0896(03)00411-5
(2003)Doi:10.1016/0008-6215(84)85115-0
(1984)Doi:10.1134/S107036321903040X
(2019)
