Bioorganic and Medicinal Chemistry Letters p. 1843 - 1848 (1996)
Update date:2022-08-03
Topics:
Shinozuka, Kazuo
Yamada, Nobuaki
Nakamura, Akiko
Ozaki, Hiroaki
Sawai, Hiroaki
Rnase H mediated degradation of RNA on the β-DNA·RNA duplex was inhibited by the presence of extra 2'-deoxypyrimidine homooligomer. The effect was dependent on the nature of the nucleobase, glycoside bond configuration, and the internucleotide linkage of the extra homooligomer used. Thus, α-anomeric 2'-deoxycytidylate phosphorothioate exhibited the most potent inhibitory effect (> 40%) on RNase H.
View MoreJiangyin Tenghua Import&Export Co.,Ltd.
Contact:+86-510-86263875
Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China
Beijing Apis Biotechnology Co., Ltd.
Contact:86-010-67856775-8551
Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Global United Biotechnology Inc.
Contact:+86-21-61618568
Address:Room 309, Building 6, NO.135, Jinyu Road, Pudong
Contact:+86-371-55981030
Address:Room 1571, Macalline Soho, No.1, Shangdu Road, Zhengzhou, Henan
Contact:86-571-61063068
Address:LINAN
Doi:10.1021/ja994522u
(2000)Doi:10.1021/ol0166909
(2001)Doi:10.1016/j.molcatb.2011.07.019
(2011)Doi:10.1016/S0968-0896(03)00411-5
(2003)Doi:10.1016/0008-6215(84)85115-0
(1984)Doi:10.1134/S107036321903040X
(2019)
