The preparation and evaluation of 1-substituted 1,2,3,4-tetrahydro- and 3,4-dihydro-β-carboline derivatives as potential antitumor agents

Article abstract of DOI:10.1248/cpb.53.32

A series of 1-substituted 1,2,3,4-tetrahydro- and 3,4-dihydro-β- carboline derivatives have been synthesized and evaluated for antitumor activity against murine P-388 and human tumor cell lines, KB-16, A-549 and HT-29. All of the compounds prepared, excep