Synthetic Communications p. 1324 - 1330 (2018)
Update date:2022-09-26
Topics:
Saravana Mani, Kailasam
Rajendran, Subramaniam Parameswaran
A facile regio and stereoselective synthesis of novel spiro[indolin-3,2′-pyrrolidin]-2-one’s have been accomplished through 1,3-dipolar cycloaddition of azomethine ylides generated in situ from the reaction of isatin and benzyl amine with quinoline bearing dipolarophiles in good yields. The synthesized compounds were well characterized through different spectroscopic techniques, such as single crystal XRD, FTIR, NMR, and mass spectral analysis.
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