Synthesis and pharmacological properties of 2-azabicyclooctane derivatives representing conformational restricted isopethidine analogues

DOI: 10.1016/0223-5234(87)90166-8

Source and publish data:

European Journal of Medicinal Chemistry p. 1 - 4 (1987)

Update date:2022-07-30

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Authors:

Cardellini, Mario

Cingolani, Gian Mario

Claudi, Francesco

Gulini, Ugo

Cantalamessa, Franco

Venturi, Fabrizio

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Article abstract of DOI:10.1016/0223-5234(87)90166-8

The synthesis and preliminary pharmacological evaluation of the epimeric 2-methyl-6-phenyl-6-carbethoxy-2-azabicyclo<2.2.2>octanes, representing conformationally restricted isopethidine analogues, are reported. 2-azabicyclo<2.2.2>octanes / isopethidine analogues / structure-activity relationship

Full text of DOI:10.1016/0223-5234(87)90166-8

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