Bioorganic and Medicinal Chemistry Letters p. 1201 - 1203 (2001)
Update date:2022-08-04
Topics:
Schoepfer, Joseph
Gay, Brigitte
End, Nicole
Muller, Evelyne
Scheffel, Gisela
Caravatti, Giorgio
Furet, Pascal
A new strategy was developed to prepare in a very efficient and convergent manner C-terminal modified tripeptides with high affinities for the Grb2-SH2 domain. Using Pd(PPh3)2Cl2 as catalyst, selected naphthyl iodides and
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