Russian Journal of Bioorganic Chemistry p. 662 - 668 (2000)
Update date:2022-07-30
Topics:
Makinsky
Kritzyn
Uljanova
Zakharova
Nevinsky
N1-Acyclic derivatives of pyrimidine bases (uracil, thymine, and cytosine) with hydrophobic polymethylene chains containing various functional groups in an ω-position of the alkyl substituent were synthesized. Their physicochemical properties and inhibitory effect on the HIV reverse transcriptase and human DNA topoisomerase I were studied.
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