Oxidative chlorination of [U-14C] phenol

Article abstract of DOI:10.1002/(SICI)1099-1344(199607)38:7<645::AID-JLCR879>3.0.CO;2-4

The preparation of [U-¹⁴C] 2,4-dichlorophenol was formerly achieved by a Sandmeyer reaction with [U-¹⁴C] 2,4-dichloroaniline but this sensitive step gave unreproductive yields in our hands. We describe another route to [U-¹⁴C] 2,4-dichlorophenol by the oxidative chlorination of [U-¹⁴C] phenol. This shorter route is safer and gives satisfactory yields. The nature of the oxidizer is discussed.