New synthetic siderophores and their β-lactam conjugates based on diamino acids and dipeptides

Article abstract of DOI:10.1016/S0968-0896(02)00044-5

Linking of siderophores to antibiotics improves the penetration and therefore increases the antibacterial activity of the antibiotics. We synthesized the acylated catecholates and hydroxamates as siderophore components for antibiotic conjugates to reduce