Discodermolide/Dictyostatin Hybrids: Synthesis and Biological Evaluation

DOI: 10.1021/ol026942l

Source and publish data:

Organic Letters p. 4443 - 4446 (2002)

Update date:2022-08-02

Topics:

Authors:

Shin, Youseung

Choy, Nakyen

Balachandran, Raghavan

Madiraju, Charitha

Day, Billy W.

Curran, Dennis P.

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Article abstract of DOI:10.1021/ol026942l

(Matrix Presented) Two hybrid analogues of discodermolide and dictyostatin (3, 26) have been designed and synthesized. These are the first macrocyclic analogues of discodermolide and biological activities were evaluated and compared with linear discodermolide analogues.

Full text of DOI:10.1021/ol026942l

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