
Journal of Medicinal Chemistry p. 194 - 197 (1991)
Update date:2022-08-03
Topics:
Iorio
Frigeni
Bowman
Harris
May
Aceto
The two optical isomers of 1-[3-(p-fluorobenzoyl)propyl]-3-methyl-4-phenyl-4-propionoxypiperidine (FPP) were obtained by resolution of (±)-r-3-methyl-4-phenyl-c-4-piperidinol followed by N-alkylation and O-propionylation. These, as well as the racemate, w
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