Common stereospecificity of opioid and dopamine systems for N-butyrophenone prodine-like compounds

Article abstract of DOI:10.1021/jm00105a029

The two optical isomers of 1-[3-(p-fluorobenzoyl)propyl]-3-methyl-4-phenyl-4-propionoxypiperidine (FPP) were obtained by resolution of (±)-r-3-methyl-4-phenyl-c-4-piperidinol followed by N-alkylation and O-propionylation. These, as well as the racemate, w