
Chemistry - A European Journal p. 17478 - 17481 (2017)
Update date:2022-08-03
Topics:
Jarava-Barrera, Carlos
Parra, Alejandro
Amenós, Laura
Arroyo, Ana
Tortosa, Mariola
Chiral α-allenols are prepared with high diastereocontrol through an unprecedented and spontaneous β-oxygen elimination of an α-epoxy vinyl boronate. Stochiometric experiments and DFT calculations support a dual role of the copper catalyst, which orchestrates the hydroboration and the syn-elimination step.
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