Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis

DOI: 10.1016/j.bmcl.2005.06.100

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 4574 - 4578 (2005)

Update date:2022-08-03

Topics:

Authors:

Liu, Weiguo

Chen, Steve

Dropinski, James

Colwell, Lawrence

Robins, Michael

Szymonifka, Michael

Hayes, Nancy

Sharma, Neelam

MacNaul, Karen

Hernandez, Melba

Burton, Charlotte

Sparrow, Carl P.

Menke, John G.

Singh, Sheo B.

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Article abstract of DOI:10.1016/j.bmcl.2005.06.100

A series of podocarpic acid amides were identified as potent agonists for Liver X receptor α and β subtypes, which are members of a nuclear hormone receptor superfamily that are involved in the regulation of a variety of metabolic pathways including chole

Full text of DOI:10.1016/j.bmcl.2005.06.100

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