Microbial Degradation of Oxadiazon by Soil Fungus Fusarium solani

Article abstract of DOI:10.1021/jf00059a035

Degradation of oxadiazon <2-tert-butyl-4-(2,4-dichloro-5-isopropoxyphenyl-Δ²-1,3,4-oxadiazolin-5-one (1)>, a preemergent soil-applied herbicide, by a soil fungus, Fusarium solani (Mortius) Sacc., has been investigated.F. solani, isolated from soil by enrichment culture technique, degraded the herbicide 1 by cometabolic process.Eleven metabolites have been isolated, out of which three metabolites (M₁, M₂, and M₃) were characterized by spectroscopic evidence.Metabolites M₁ and M₃ are reported for the first time as metabolites of oxadiazon.The main metabolic pathways involve oxadiazoline ring cleavage without dechlorination reaction. - Keywords: degradation; cometabolism; metabolic pathway; oxadiazon; Fusarium solani.