Synthesis and conformational study of water-soluble, rigid, rodlike oligopiperidines

Article abstract of DOI:10.1002/anie.200502991

An oligomeric backbone of piperidine rings can be synthesized by solution or solid-phase synthesis. These oligomers adopt well-defined, rodlike structures with all the piperidine residues in chair conformations (see picture) both in solution (D₂O, CD₃OD) and the solid state. (Figure Presented).