Tetrahedron Letters p. 4221 - 4224 (1982)
Update date:2022-08-03
Topics:
Chin, Jik
Breslow, Ronald
In neutral aqueous acetonitrile, N-o-hydroxybenzyl-2,3-dimethylmaleamic acid is rapidly converted to N-o-hydroxybenzyl-2,3-dimethylmaleimide, while N-propyl-N-o-hydroxybenzyl-2,3-dimethylmaleamic acid is converted to dimethylmaleic anhydride; both reactions are catalyzed by the phenolic groups.
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