2-(Aminomethyl)phenols, a New Class of Saluretic Agents. 6. Effects of N,O-Spiroannulation and Subsequent Quaternization

DOI: 10.1021/jm00358a024

Source and publish data:

Journal of Medicinal Chemistry p. 585 - 590 (1983)

Update date:2022-08-03

Topics:

Authors:

Stokker, G.E.

Schultz, E.M.

Smith, R.I.

Cragoe, E.J.

Russo, H.F.

et al. et al.

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Article abstract of DOI:10.1021/jm00358a024

The syntheses of a number of 3,4-dihydrospiro-2H-1,3-benzoxazines and their corresponding benzoxazinium salts are reported.The saluretic effects displayed by these N,O-spiroannulated 2-(aminomethyl)phenols appear to be, in part, inversely related to their

Full text of DOI:10.1021/jm00358a024

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