Journal of Medicinal Chemistry p. 1873 - 1879 (1989)
Update date:2022-08-04
Topics: Chemical Synthesis Selective Antagonists Receptor binding assay Functional assay
Jacobson, Kenneth A.
Kiriasis, Leonidas
Barone, Suzanne
Bradbury, Barton J.
Kammula, Udai
et al.
Sulfur-containing analogues of 8-substituted xanthines were prepared in an effort to increase selectivity or potency as antagonists at adenosine receptors.Either cyclopentyl or various aryl substituents were utilized at the 8-position, because of the asso
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