Sulfur-Containing 1,3-Dialkylxanthine Derivatives as Selective Antagonists at A1-Adenosine Receptors

Article abstract of DOI:10.1021/jm00128a031

Sulfur-containing analogues of 8-substituted xanthines were prepared in an effort to increase selectivity or potency as antagonists at adenosine receptors.Either cyclopentyl or various aryl substituents were utilized at the 8-position, because of the asso