Journal of Medicinal Chemistry p. 309 - 312 (1978)
Update date:2022-08-04
Topics:
Helsley
Strupczewski
Woodward
A series of 3-[2-(phenoxypiperidyl)ethyl]indoles was synthesized and evaluated for hypotensive activity in the spontaneous hypertensive rat. Maximum hypotensive activity appeared when the phenoxy substituent was para substituted and occupied the 4 position of the piperidine ring.
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