ALKYLIDENEDIPHOSPHONATES ET VINYLPHOSPHONATES: UNE DEMARCHE SYNTHETIQUE SELECTIVE PAR VOIE CARBANIONIQUE

Article abstract of DOI:10.1016/0022-328X(86)80147-4

Phosphonoalkylation of acylchloro-phosphates or -phosphinates in the presence of excess lithium diisopropylamide leads to direct generation of lithiated methylenediphosphonate anions.This stable type of anion can be either protonated in acidic medium to provide tetrasubstituted methylenediphosphonate or alkylated.When aliphatic or aromatic aldehydes are added spontaneous formation of vinylphosphonates is observed.This process is a simple and convenient route to diphosphonic as well as to vinylphosphonic compounds.