Journal of Medicinal Chemistry p. 5094 - 5111 (2014)
Update date:2022-08-15
Topics:
Mahalingam, Poornachandran
Takrouri, Khuloud
Chen, Ting
Sahoo, Rupam
Papadopoulos, Evangelos
Chen, Limo
Wagner, Gerhard
Aktas, Bertal H.
Halperin, Jose A.
Chorev, Michael
The 4EGI-1 is the prototypic inhibitor of eIF4E/eIF4G interaction, a potent inhibitor of translation initiation in vitro and in vivo and an efficacious anticancer agent in animal models of human cancers. We report on the design, synthesis, and in vitro ch
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