On the chemoselectivity and mechanism of desilylation of tert- butyldimethylsilyl ethers with TMSOTf

DOI: 10.1016/S0040-4039(99)00523-7

Source and publish data:

Tetrahedron Letters p. 3643 - 3646 (1999)

Update date:2022-08-04

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Authors:

Hunter, Roger

Hinz, Wolfgang

Richards, Philip

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Article abstract of DOI:10.1016/S0040-4039(99)00523-7

A modified literature procedure is presented for desilylating primary and secondary tert-butyldimethylsilyl ethers involving TMSOTf followed by breakdown of the bis-silyloxonium ion in methanol. The chemoselectivity of the process with respect to TBDPS, T

Full text of DOI:10.1016/S0040-4039(99)00523-7

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