On the chemoselectivity and mechanism of desilylation of tert- butyldimethylsilyl ethers with TMSOTf

DOI: 10.1016/S0040-4039(99)00523-7

Source and publish data:

Tetrahedron Letters p. 3643 - 3646 (1999)

Update date:2022-08-04

Topics:

Authors:

Hunter, Roger

Hinz, Wolfgang

Richards, Philip

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00523-7

A modified literature procedure is presented for desilylating primary and secondary tert-butyldimethylsilyl ethers involving TMSOTf followed by breakdown of the bis-silyloxonium ion in methanol. The chemoselectivity of the process with respect to TBDPS, T

Full text of DOI:10.1016/S0040-4039(99)00523-7

Products guided by the article

Product name:Benzoic acid (4R,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester

Cas No:69434-38-4

R&D Labs maybe for 69434-38-4

Suzhou HeChuang Chemical Co.,Ltd.

Contact:+86-512-88800520

Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Luzhou North Chemical Co., Ltd.

Contact:+86-830-2796784；+86-830-2796776

Address:Gaoba, Longmatan District, Luzhou, Sichuan Province
Phantom-pharma

Contact:

Address:
Hangzhou Haiqiang Chemical Co.,Ltd.

Contact:+86-571-86960370

Address:Add: 5/F, Around Town North Road,No. 10, Hangzhou, Zhejiang,China
Borun Chemical Co.,Ltd.

Contact:+86-574- 87178138; 87297407

Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China

Relevant to this article

Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist

Doi:10.1021/jm050235r
(2005)
Doi:10.1093/gerona/56.4.B163
(1954)
Doi:10.1016/S0031-9422(00)94602-8
(1978)
Nucleophilic substitution in 4-bromo-5-nitrophthalodinitrile: VIII. Synthesis of 4-(benzotriazol-1-yl)-5-[4-(1-methyl-1-phenylethyl)phenoxy] phthalodinitrile and phthalocyanines on its basis

Doi:10.1134/S1070363207090216
(2007)
Doi:10.14233/ajchem.2018.21192
(2018)
[3+2]-cycloaddition reaction between chiral oxaziridines and nitriles: Enantioselective synthesis of 2,3-dihydro-1,2,4-oxadiazoles

Doi:10.1055/s-0030-1258175
(2010)

Article Doi