On the chemoselectivity and mechanism of desilylation of tert- butyldimethylsilyl ethers with TMSOTf

DOI: 10.1016/S0040-4039(99)00523-7

Source and publish data:

Tetrahedron Letters p. 3643 - 3646 (1999)

Update date:2022-08-04

Topics:

Authors:

Hunter, Roger

Hinz, Wolfgang

Richards, Philip

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00523-7

A modified literature procedure is presented for desilylating primary and secondary tert-butyldimethylsilyl ethers involving TMSOTf followed by breakdown of the bis-silyloxonium ion in methanol. The chemoselectivity of the process with respect to TBDPS, T

Full text of DOI:10.1016/S0040-4039(99)00523-7

Products guided by the article

Product name:Benzoic acid (4R,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester

Cas No:69434-38-4

R&D Labs maybe for 69434-38-4

Shenzhen HwaGen Pharmaceutical Co., Ltd

website:http://www.rafflespt.com

Contact:+86-752-5538396

Address:Guangdong Huizhou China
Tianjin Hedong Red Cliff Chemical Reagent Factory

Contact:+86-022-84780548

Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Richest Group Ltd.

Contact:+86 21 5017 5386

Address:No 999,Jiangyue Rd, Minhang Dist ,201114,Shanghai ,China
Shandong Xinke Petrochemical Co., Ltd.

Contact:+86-546-7277016

Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China

Relevant to this article

Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist

Doi:10.1021/jm050235r
(2005)
Doi:10.1093/gerona/56.4.B163
(1954)
Doi:10.1016/S0031-9422(00)94602-8
(1978)
Nucleophilic substitution in 4-bromo-5-nitrophthalodinitrile: VIII. Synthesis of 4-(benzotriazol-1-yl)-5-[4-(1-methyl-1-phenylethyl)phenoxy] phthalodinitrile and phthalocyanines on its basis

Doi:10.1134/S1070363207090216
(2007)
Doi:10.14233/ajchem.2018.21192
(2018)
[3+2]-cycloaddition reaction between chiral oxaziridines and nitriles: Enantioselective synthesis of 2,3-dihydro-1,2,4-oxadiazoles

Doi:10.1055/s-0030-1258175
(2010)

Article Doi