Journal of Pharmaceutical Sciences p. 275 - 277 (1984)
Update date:2022-08-03
Topics:
Gigot
Penninckx
Two peptide forms of the antitumor transition state analogue N-phosphonoacetyl-L-aspartic acid (N2-phosphonoacetyl-N4-glycylglycinamidoethyl-L-asparagine and N1-glycylglycinamidoethyl-N2-phosphonoacetyl-L-isoasparagine) have been synthesized to obtain potential medicinal agents useful as prodrugs or in a lysosomotropic carrier approach. The bridging unit, ethylenediamine, used for synthetic purposes might be of general interest.
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Doi:10.1021/acs.joc.9b01015
(2019)Doi:10.1021/jo0358877
(2004)Doi:10.1016/0008-6215(90)84083-7
(1990)Doi:10.1021/ja00520a025
(1979)Doi:10.1016/S0008-6215(00)85199-X
(1980)Doi:10.1021/ja00517a034
(1979)
