An interdisciplinary approach to the design of new structures active at the β-adrenergic receptor. Aliphatic oxime ether derivatives

Article abstract of DOI:10.1021/jm00380a001

On the basis of results previously obtained from structural and theoretical studies on β-adrenergic drugs, a series of aliphatic oxime ether derivatives (AOEDs) was synthesized. As expected, pharmacological in vitro tests showed that compounds examined ex