Thermochemical Identification of the Structural Factors Responsible for the Thermodynamic Instability of 3',5'-Cyclic Nucleotides

Article abstract of DOI:10.1021/ja00525a033

The enthalpies of hydrolysis of several cyclic phosphate diesters which can be considered to be structural analogues of the trans-fused trimethylene phosphate-ribofuranoside ring system of adenosine 3',5'-cyclic phosphate have been determined by microcalo