Iron-catalyzed benzylation reaction of arenes with benzyl thiocyanates

Article abstract of DOI:10.1055/s-0031-1290343

A novel, regioselective protocol for the synthesis of diphenylmethane derivatives has been developed by using iron-catalyzed Friedel-Crafts reaction of arenes with benzyl thiocyanates. In the presence of FeBr₃, a variety of benzyl thiocyanates underwent the reaction with arenes to selectively afford the corresponding diarylmethane derivatives in moderate to high yields. Georg Thieme Verlag Stuttgart · New York.