Journal of Medicinal Chemistry p. 2052 - 2059 (1990)
Update date:2022-08-02
Topics:
MacLeod
Baker
Freedman
Patel
Merchant
Roe
Saunders
A series of novel 1,2,4-thiadiazoles bearing a mono- or bicyclic amine at C5 were prepared. Quinuclidine and 1-azabicyclo[2.2.1]heptane derivatives were synthesized by reaction of the lithium enolate of the 3-methoxycarbonyl compounds followed by ester hy
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