Journal of the Chemical Society. Perkin transactions I p. 481 - 486 (1980)
Update date:2022-08-02
Topics:
Bajwa, Joginder S.
Sykes, Peter J.
The reaction of 3-aminopyrazole and its 4-cyano-derivative with 2-hydroxymethylene-3-oxo-steroids gave a mixture of angularly fused and linearly fused products, androst-2-eno<2,3-g>- and androstano<3,2-f>-pyrazolo<1,5-a>pyrimidines, respectively.However, the condensation of 3-amino-4-cyano-5-cyanomethylpyrazole with 2-hydroxymethyl-3-oxo-steroids gave only angularly fused products, namely, androst-2-eno<2,3-g>pyrazolo<1,5-a>pyrimidines.The reaction of 3-aminopyrazole and its derivatives with a 2-hydroxymethylene-Δ4-3-oxo-steroid and 16-hydroxymethylene-17-oxo-steroids also afforded only the angularly fused products, androst-2,4-dieno<2,3-g>- and androst-16-eno<16,17-g>-pyrazolo<1,5-a>pyrimidines, respectuvely.The structures of all these compounds were established by i.r., u.v., and 1H and 13C n.m.r. spectroscopy.
View MoreDayang Chem (Hangzhou) Co.,Ltd.
website:http://www.dycnchem.com
Contact:+86-571-88938639
Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China
Hebei Fulong Import & Export Co., Ltd.
Contact:86-311-87795661
Address:15A19 Zhongyuan Building,368 Youyi North Street,Shijiazhuang 050070,China
Contact:+86-21-56338808
Address:799 Dunhuang Road, Putuo
Changsha Huajing Powdery Material Technological Co., Ltd.
Contact:86-731-88879686
Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Contact:+86-512-56795332
Address:No227 Shuanglong Rd, Fenghuang, Zhangjiagang
Doi:10.1021/ja047498f
(2004)Doi:10.1515/HC.2001.7.1.61
(2001)Doi:10.1016/S0040-4020(01)98803-9
(1984)Doi:10.1002/hlca.19800630306
(1980)Doi:10.1023/B:RUGC.0000016026.56938.f2
(2003)Doi:10.1246/bcsj.53.1625
(1980)
