Journal of the Chemical Society. Perkin transactions I p. 481 - 486 (1980)
Update date:2022-08-02
Topics:
Bajwa, Joginder S.
Sykes, Peter J.
The reaction of 3-aminopyrazole and its 4-cyano-derivative with 2-hydroxymethylene-3-oxo-steroids gave a mixture of angularly fused and linearly fused products, androst-2-eno<2,3-g>- and androstano<3,2-f>-pyrazolo<1,5-a>pyrimidines, respectively.However, the condensation of 3-amino-4-cyano-5-cyanomethylpyrazole with 2-hydroxymethyl-3-oxo-steroids gave only angularly fused products, namely, androst-2-eno<2,3-g>pyrazolo<1,5-a>pyrimidines.The reaction of 3-aminopyrazole and its derivatives with a 2-hydroxymethylene-Δ4-3-oxo-steroid and 16-hydroxymethylene-17-oxo-steroids also afforded only the angularly fused products, androst-2,4-dieno<2,3-g>- and androst-16-eno<16,17-g>-pyrazolo<1,5-a>pyrimidines, respectuvely.The structures of all these compounds were established by i.r., u.v., and 1H and 13C n.m.r. spectroscopy.
View MoreContact:13357117572
Address:No.149 Shiji dadao Road.
Anhui Asahikasei Chemical Co., Ltd
Contact:86-551-4259770
Address:No. 88 Linquan Road Hefei Anhui China
Xiamen Hisunny Chemical Co.,Ltd
website:http://www.hisunnychem.com
Contact:+86-592-3327115
Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China
Suzhou Jingye Medicine & Chemical Co., Ltd
Contact:+86-512-66658588
Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
Lonzeal Pharmaceuticals Co., Ltd.
website:http://www.lonzeal.com
Contact:+86-13381011962
Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Doi:10.1021/ja047498f
(2004)Doi:10.1515/HC.2001.7.1.61
(2001)Doi:10.1016/S0040-4020(01)98803-9
(1984)Doi:10.1002/hlca.19800630306
(1980)Doi:10.1023/B:RUGC.0000016026.56938.f2
(2003)Doi:10.1246/bcsj.53.1625
(1980)
