An Effective Chelating Agent for Labelling of Monoclonal Antibody with 212Bi for &α-Particle Mediated Radioimmunotherapy

DOI: 10.1039/c39910001169

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1169 - 1170 (1991)

Update date:2022-08-02

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Authors:

Brechbiel, Martin W.

Pippin, C. Greg

McMurry, Thomas J.

Milenic, Diane

Roselli, Mario

et al. et al.

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Article abstract of DOI:10.1039/c39910001169

The ligand N-<2-amino-3-(p-isothiocyanatophenyl)propyl>-(+/-)trans-1,2-diaminocyclohexane-N,N',N''-pentaacetic acid has been synthesized and linked to lgG and to monoclonal antibody B72.3 and labelled with 206Bi and 212Bi to demonstrate the in vivo stabil

Full text of DOI:10.1039/c39910001169

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