Antimalarials. 12. Preparation of Carbon Isosteres of Selected 4-Pyridinemethanols as Suppressive Antimalarials

Article abstract of DOI:10.1021/jm00185a009

Four carbon isosteres related to the highly active 4-pyridylcarbinolamines were prepared and evaluated for suppressive antimalarial activity against Plasmodium berghei in mice.Three of the four examples possessed significant activity but were approximatel