Synthesis of analogues of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin

DOI: 10.1021/jm00175a006

Source and publish data:

Journal of Medicinal Chemistry p. 27 - 33 (1980)

Update date:2022-09-26

Topics:

Authors:

Rich Rich

Sun Sun

Ulm Ulm

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00175a006

Analogues of the carboxyl protease inhibitor, pepstatin, were synthesized from optically pure forms of N-(tert-butoxycarbonyl)-4-amino-3-hydroxy-6-methylheptanoic acid (Boc-Sta), and the inhibition of pepsin and renin was determined. In addition, the new

Full text of DOI:10.1021/jm00175a006

Products guided by the article

Product name:isovaleryl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoyl-L-alanyl isoamylamide

Cas No:75846-13-8

R&D Labs maybe for 75846-13-8

Jiangxi Dongbang Pharmaceutical Co., Ltd.

Contact:+86-795-4433603, 4433388

Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
Xinjiang Fufeng Biotechnologies Co., Ltd.

Contact:+86-539-7287111

Address:GANQUANPU INDUSTRIAL PARK, ECONOMIC AND TECHNOLOGICAL DEVELOPMENT AREA (TOUTUNHE DISTRICT) OF URUMQI
Second Pharma Co., Ltd

Contact:+86-575-82733999 0575-82732999

Address:hangzhou gulf fine chemical zone,shangyu city,zhejiang province
JIANGXI ZHANGFENG CHEMICAL CO., LTD.

Contact:+86-0799-3413066

Address:Xiyuan village, Xiabu Town, Xiangdong District
Jiangyin Tenghua Import&Export Co.,Ltd.

Contact:+86-510-86263875

Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China

Relevant to this article

Synthesis of advanced intermediates of lennoxamine analogues

Doi:10.1055/s-2007-965950
(2007)
Oxalyl-CoA Decarboxylase Enables Nucleophilic One-Carbon Extension of Aldehydes to Chiral α-Hydroxy Acids

Doi:10.1002/anie.201915155
(2020)
The copper(II) complex with two didentate schiff base ligands. The unique rearrangment that proceeds under alcohol vapor in the solid state to construct noninclusion structure

Doi:10.1246/cl.2008.78
(2008)
STUDIES ON TERPENES-7. A SHORT ROUTE TO A PENTALENOLACTONE E PRECURSOR

Doi:10.1016/0040-4020(81)80019-1
(1981)
Comparative study of the trypanocidal activity of the methyl 1-nitrophenyl-1,2,3,4-9H-tetrahydro-β-carboline-3-carboxylate derivatives and benznidazole using theoretical calculations and cyclic voltammetry

Doi:10.1016/j.ejmech.2008.03.044
(2009)
New approach to the synthesis of 2'(3')-0-aminoacyl oligoribonucleotides

Doi:10.1021/jo00233a015
(1987)

Article Doi