Aporphines. 35. Synthesis of (R)-(-)- and (S)-(+)-Apomorphine from Thebaine and (+)-Bulbocapnine

DOI: 10.1021/jo00326a058

Source and publish data:

Journal of Organic Chemistry p. 2830 - 2831 (1981)

Update date:2022-09-26

Topics:

Authors:

Ram, Vishnu J.

Neumeyer, John L.

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Article abstract of DOI:10.1021/jo00326a058

A practical method for the synthesis of (-)-apomorphine and (-)-N-n-propylnorapomorphine from the opioid thebaine is presented.The method is also applicable to the transformation of (+)-bulbocapnine to (+)-apomorphine.

Full text of DOI:10.1021/jo00326a058

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