Highly enantioselective synthesis of β-hydroxysulfonamides by asymmetric transfer hydrogenation

DOI: 10.1016/j.tetlet.2010.12.054

Source and publish data:

Tetrahedron Letters p. 907 - 909 (2011)

Update date:2022-08-03

Topics:

Authors:

Geng, Zhicong

Wu, Yun Wu, Yun

Miao, Shifeng

Shen, Zongxuan

Zhang, Yawen

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Article abstract of DOI:10.1016/j.tetlet.2010.12.054

A series of optically active β-hydroxy sulfonamides were synthesized for the first time by asymmetric transfer hydrogenation of the corresponding β-ketosulfonamides using the Ru-TsDPEN-HCOOH-Et₃N catalytic system, in excellent yields (up to 95%

Full text of DOI:10.1016/j.tetlet.2010.12.054

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