Chemistry of Heterocyclic Compounds p. 732 - 735 (1981)
Update date:2022-09-26
Topics:
Bogatskii, A. V.
Ivanova, R. Yu.
Andronati, S.A.
Zhilina, Z. I.
The alkaline hydrolysis, amidation, and methylation of 4,5-dihydropyrrolo<1,2,3-e,f><1,5>benzodiazepin-6(7H)-one derivatives under various conditions were investigated.The ionization constants (pKα) for 1,2-dimethyl-4,5-dihydro<1,2,3-e,f,><1,5>benzodiazepin-6(7H)-one were calculated by the Hammett indicator method, and two values, viz. pKα1 = -2.37 and pKα2 = 5.53, which were ascribed to protonation of the diazepine ring and the indole ring of the molecule, respectively, were obtained.
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Doi:10.1016/S0040-4039(01)81895-5
(1981)Doi:10.1002/chem.200400322
(2004)Doi:10.1246/cl.1981.615
(1981)Doi:10.1021/ol048578r
(2004)Doi:10.1016/S0040-4039(01)82923-3
(1981)Doi:10.1021/ja00405a067
(1981)
