
Helvetica Chimica Acta p. 2519 - 2524 (1983)
Update date:2022-08-04
Topics:
Fehr, Charles
Treatment of the sulfonyl ketones 1 a and 1 b with potassium t-butoxide in toluene or with potassium hydroxyde in toluene/dimethyl sulfoxide affords in high yield the bicyclic dienes 3 a and 3 b, importantbprecursors for exaltoneR and (+/-)-muscone.An Application of this novell pentaannulation sequence is demonstrated for the solfonyl ketones 6, 10, and 14.An intermolecular variant is exemplified by the synthesis of diene 22.
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