Synthesis of Polycyclic Homocyclopropylcarbinols by Reductive Cyclization of Bromocyclopropyl Epoxides

Article abstract of DOI:10.1021/jo00138a003

A new synthetic route to polycyclic homocyclopropylcarbinols has been realized by lithiation of bromocyclopropyl epoxides with n-butyllithium and subsequent intramolecular attack of the metalated cyclopropane ring onto the epoxide.A series of seven bromoc