A NEW SYNTHESIS OF DEGLYCO-BLEOMYCIN A2 AIMING AT THE TOTAL SYNTHESIS OF BLEOMYCIN

DOI: 10.1016/S0040-4039(00)86880-X

Source and publish data:

Tetrahedron Letters p. 529 - 532 (1982)

Update date:2022-08-03

Topics:

Authors:

Saito, Sei-ichi

Umezawa, Yoji

Morishima, Hajime

Takita, Tomohisa

Umezawa, Hamao

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)86880-X

An improved route to synthesize deglyco-bleomycin A2, the aglycon of bleomycin A2, aiming at the total synthesis of bleomycin is described.The new route is characterized by the stepwise elongation of the amino acid constituents and the use of a thiol este

Full text of DOI:10.1016/S0040-4039(00)86880-X

Products guided by the article

Product name:{3-[(2'-{2-[(2S,3R)-2-((2S,3S,4R)-4-Benzyloxycarbonylamino-3-hydroxy-2-methyl-pentanoylamino)-3-hydroxy-butyrylamino]-ethyl}-[2,4']bithiazolyl-4-carbonyl)-amino]-propyl}-dimethyl-sulfonium; chloride

Cas No:82704-02-7

R&D Labs maybe for 82704-02-7

Changzhou Sunsheng Chem Co., Ltd

Contact:+1-(989)-854-0648

Address:No. 28 Yinshan Rd., Xixiashu Industrial Park
taizhou creating bio-pharm co.,ltd.

Contact:+86- 576- 88827176

Address:715 room ,unit A.junyue Building,Jiaojiang,Taizhou,Zhejiang,China
Shandong Topscience Biotech Co., Ltd.

Contact:0633-2619278

Address:No. 98 Lanshan West Road, Lanshan District, Rizhao, Shandong Province, P.R. of China
Nanjing Samwon International Limited

Contact:+86-25-84873444

Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Taizhou YOJOY Chemical Co., Ltd.

Contact:13857143241

Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China

Relevant to this article

Synthesis of pyrazolyl-2-pyrazolines by treatment of 3-(3-aryl-3- oxopropenyl)chromen-4-ones with hydrazine and their oxidation to bis(pyrazoles)

Doi:10.1002/ejoc.200400465
(2004)
Use of malonic acid derivatives for the constuction of substituted side chains in the position 17β of steroids

Doi:10.1135/cccc19821240
(1982)
THE REGIOSELECTIVITY OF THE REDUCTIVE RING-CLEAVAGE OF THE ACETAL RING OF 4,6-O-BENZYLIDENEHEXOPYRANOSIDES

Doi:10.1016/S0008-6215(00)82220-X
(1982)
Coupling of Diazopurines, a Curious Steric Effect in a Free Radical Reaction

Doi:10.1021/jo00146a013
(1982)
Chemistry of Ambergris. 1. A Short Synthesis of (+/-)-δ-Ambrinol

Doi:10.1021/jo00145a040
(1982)
Synthesis and cytotoxic activity of hydroxylated derivatives of olivacine in relation with their biotransformation

Doi:10.1021/jm00383a004
(1985)

Article Doi