A NEW SYNTHESIS OF DEGLYCO-BLEOMYCIN A2 AIMING AT THE TOTAL SYNTHESIS OF BLEOMYCIN

DOI: 10.1016/S0040-4039(00)86880-X

Source and publish data:

Tetrahedron Letters p. 529 - 532 (1982)

Update date:2022-08-03

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Authors:

Saito, Sei-ichi

Umezawa, Yoji

Morishima, Hajime

Takita, Tomohisa

Umezawa, Hamao

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Article abstract of DOI:10.1016/S0040-4039(00)86880-X

An improved route to synthesize deglyco-bleomycin A2, the aglycon of bleomycin A2, aiming at the total synthesis of bleomycin is described.The new route is characterized by the stepwise elongation of the amino acid constituents and the use of a thiol este

Full text of DOI:10.1016/S0040-4039(00)86880-X

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