Efficient syntheses of N-alkyl-3-hydroxy-2-methyl-4(1H)-pyridinones from carbohydrate precursors

Article abstract of DOI:10.1080/00397919908086062

N-alkyl-3-hydroxy-2-methyl-4(1H)-pyridinones can be synthesised in reasonable yield from either 1-(3-hydroxy-2-furanyl)ethanone or O- galactosylisomaltol. Since these carbohydrate precursors can be produced from the disaccharide, α-D-lactose, a simple and inexpensive transformation into pyridinones is possible.

Full text of DOI:10.1080/00397919908086062

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Efficient Syntheses of
N-Alkyl-3-hydroxy-2-
methyl-4(1H)-pyridinones From
Carbohydrate Precursors
Raymond C. Fox a & Paul D. Taylor b
a Department of Chemistry , University College
London , 20 Gordon Street, London, WC1H OAJ, UK
b Transgenomic Inc., Concourse Drive , San Jose, CA,
95131, USA
Published online: 17 Sep 2007.
To cite this article: Raymond C. Fox & Paul D. Taylor (1999) Efficient Syntheses of N-
Alkyl-3-hydroxy-2-methyl-4(1H)-pyridinones From Carbohydrate Precursors, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 29:6, 989-1001, DOI: 10.1080/00397919908086062
To link to this article: http://dx.doi.org/10.1080/00397919908086062
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