Tetrahedron p. 2051 - 2054 (1982)
Update date:2022-09-26
Topics:
Yuan, Sun-Shine
Ajami, Alfred M.
(R,S)-serine-1-(13)C was incubated in a culture of Escherichia coli cells to produce (S)-tryptophan-1-(13)C.Bromoacetyl bromide-2-(13)C was converted to bromoacetanilide and cyclization of the anilide, followed by reduction and dehydrogenation furnished indole-3-(13)C.Indole-(15)N was synthesized by known sequences.These (13)C and (15)N isotomers of indole were converted by commercially available, lyophilized E. coli to furnish (S)-tryptophan-γ-(13)C and (S)-tryptophan-indole-(15)N, respectively.
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Doi:10.1007/BF00503207
(1982)Doi:10.1039/c8ob01064a
(2018)Doi:10.1021/jm049036i
(2005)Doi:10.1246/bcsj.55.3025
(1982)Doi:10.1016/j.bmcl.2007.11.124
(2008)Doi:10.1016/j.bmc.2004.11.020
(2005)