Synthesis and Antiviral Activity of Water-Soluble Esters of Acyclovir guanine>

DOI: 10.1021/jm00358a029

Source and publish data:

Journal of Medicinal Chemistry p. 602 - 604 (1983)

Update date:2022-08-04

Topics:

Authors:

Colla, Leon

Clercq, Erik De

Busson, Roger

Vanderhaeghe, Hubert

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00358a029

Several water-soluble ester derivatives of acyclovir <9-<(2-hydroxyethoxy)methyl>guanine>, i.e., the 2'-O-glycyl-, 2'-O-α-alanyl, 2'-O-β-alanyl- and 2'-O-3-carboxypropionyl esters, were synthesized and evaluated for their antiviral activity in cell cultur

Full text of DOI:10.1021/jm00358a029

Products guided by the article

Product name:3-Benzyloxycarbonylamino-propionic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

Cas No:84499-70-7

R&D Labs maybe for 84499-70-7

Jingzhou TianHe Sci&Tech Chemical Co., Ltd.

Contact:86-716-8331612

Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone
Changzhou Litong Chemical Co., Ltd.

website:http://www.litonchem.com/

Contact:+86-519-86301238

Address:Laoba Rd, Hutang town Changzhou Jiangsu
HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA

Relevant to this article

Adducts of aluminum and gallium trichloride with a N-heterocyclic carbene and an adduct of aluminum trichloride with a thione

Doi:10.1002/ejic.200400247
(2004)
PHOTOCHEMICAL REACTION OF ALCOHOLS - II. IRRADIATION OF AROMATIC ALCOHOLS

Doi:10.1016/0040-4020(82)85088-6
(1982)
Synthesis of isomeric angularly annealed dinaphthoporphyrin systems: Examination of the relative positioning and orientation of ring fusion as factors influencing the porphyrin chromophore

Doi:10.1021/jo040269r
(2005)
Zinc (II)-mediated selective O-benzylation of 2-Oxo-1,2-dihydropyridines systems

Doi:10.3390/molecules23071784
(2018)
Synthetic efforts toward the C22-C36 subunit of halichondrin B utilizing local and imposed symmetry

Doi:10.1021/ol0473400
(2005)
A CONVERGENT TOTAL SYNTHESIS OF (-)-ANAMARINE FROM D-GLUCOSE

Doi:10.1016/S0040-4039(00)95645-4
(1987)

Article Doi