Bioorganic and Medicinal Chemistry p. 3692 - 3706 (2019)
Update date:2022-08-15
Topics:
Chino, Ayaka
Honda, Shugo
Morita, Masataka
Yonezawa, Koichi
Hamaguchi, Wataru
Amano, Yasushi
Moriguchi, Hiroyuki
Yamazaki, Mayako
Aota, Masaki
Tomishima, Masaki
Masuda, Naoyuki
Phosphodiesterase 10A (PDE10A) inhibitors were designed and synthesized based on the dihydro-imidazobenzimidazole scaffold. Compound 5a showed moderate inhibitory activity and good permeability, but unfavorable high P-glycoprotein (P-gp) liability for bra
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(2018)Doi:10.1134/S1070363217060275
(2017)Doi:10.1055/s-0034-1381044
(2015)Doi:10.1016/j.tetlet.2005.01.067
(2005)Doi:10.1016/j.bmcl.2005.01.024
(2005)Doi:10.1016/S0040-4039(00)88366-5
(1982)