Synlett p. 343 - 345 (2005)
Update date:2022-09-26
Topics:
Boukouvalas, John
Pouliot, Martin
The first synthesis of cadiolide B has been achieved in 6 steps and 42% overall yield from 4-bromo-2(5H)-furanone. The pathway involves sequential, regiocontrolled introduction of the three furanone substituents by means of aldol reactions and Suzuki cros
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