Novel glycine transporter type-2 reuptake inhibitors. Part 2: β- and γ-amino acid derivatives

DOI: 10.1016/j.bmc.2004.05.043

Source and publish data:

Bioorganic and Medicinal Chemistry p. 4493 - 4509 (2004)

Update date:2022-08-05

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Authors:

Wolin, Ronald L.

Santillán Jr., Alejandro

Barclay, Tristin

Tang, Liu

Venkatesan, Hariharan

Wilson, Sandy

Lee, Doo Hyun

Lovenberg, Timothy W.

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Article abstract of DOI:10.1016/j.bmc.2004.05.043

Several β- and γ-amino acid derivatives were prepared as glycine transport inhibitors and their ability to block the uptake of [ ¹⁴C]-glycine in COS7 cells transfected with human glycine transporter-2 (hGlyT-2) were evaluated. A range of lipoph

Full text of DOI:10.1016/j.bmc.2004.05.043

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