1-(4-Nitrophenoxycarbonyl)-7-pyridin-4-yl indolizine: A new versatile fluorescent building block. Application to the synthesis of a series of fluorescent β-cyclodextrins

Article abstract of DOI:10.1016/j.tet.2005.02.063

The synthesis of a series of new fluorescent building blocks 1a-d incorporating a pyridinoindolizine unit and two potentially reactive sites is described. The reaction of 1a-d with the mono-6-amino-6-deoxy-β- cyclodextrin provides the corresponding fluorescent water soluble hosts 2a-d in good yield. The sensor properties of 2a-d in the presence of 1-adamantanol is described.