SYNTHESIS OF (4aR,9aS,9bR)- AND (4aR,9aS,9bS)-4a,6,6,9a-TETRAMETHYL-trans-PERHYDROINDANOPYRANS

Article abstract of DOI:10.1007/BF00513253

C_(9b)-Epimeric (4aR,9aS)-4a,6,6,9a-tetramethyl-trans-perhydroindano<2,1-c>pyrans, which have the odor of ambergris, were synthesized by dehydration of the corresponding glycols.It was establieshed that a mixture of epimeric (3a)> (8aS,8bR)-5,5,8a-trimethyl-3a-ethyl-trans-perhydroindano<2,1-b>furans is formed along with a trans-perhydroindano<2,1-c>pyran derivative in the acidic dehydration of (1R,2R,7aS)-2,4,4,7a-tetramethyl-1-(2-hydroxyethyl)-2-hydroxymethyl-trans-hydrindan.